Brief Information of the Compound and Protein
Compound Name
3-[[2-(1H-pyrrol-2-yl)quinazolin-4-yl]amino]benzonitrile
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PubChem ID
CID: 155533532
Canonical SMILES
N#Cc1cccc(Nc2nc(nc3ccccc23)-c2ccc[nH]2)c1
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Compound Formula C19H13N5
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  2
1
IC50 = 7.98 nM
   TI
   LI
   LO
   TS
2
IC50 = 156 nM
   TI
   LI
   LO
   TS