Brief Information of the Compound and Protein
Compound Name
3-[(2-thiophen-2-ylquinazolin-4-yl)amino]benzonitrile
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PubChem ID
CID: 155534490
Canonical SMILES
N#Cc1cccc(Nc2nc(nc3ccccc23)-c2cccs2)c1
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Compound Formula C19H12N4S
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  2
1
IC50 = 45.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 178 nM
   TI
   LI
   LO
   TS