Brief Information of the Compound and Protein
Compound Name
 Compound Info 
15-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-11-oxa-3,4,6,19,24-pentazatetracyclo[18.3.1.02,6.012,17]tetracosa-1(24),2,4,12(17),13,15,20,22-octaen-18-one
    Show/Hide
 PubChem ID
CID: 142411827
Canonical SMILES
CN(C)CCn1cc(cn1)-c1ccc2OCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3
    Show/Hide
Compound Formula C25H28N8O2
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase kinase kinase 5
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE11 family
Uniprot ID
Q99683
Gene Name
MAP3K5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 148 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6 nM