Brief Information of the Compound and Protein
Compound Name
12-oxa-3,4,6,20,25-pentazatetracyclo[19.3.1.02,6.013,18]pentacosa-1(25),2,4,13,15,17,21,23-octaen-19-one
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PubChem ID
CID: 142412072
Canonical SMILES
O=C1Nc2cccc(n2)-c2nncn2CCCCCOc2ccccc12
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Compound Formula C19H19N5O2
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 5
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE11 family
Uniprot ID
Q99683
Gene Name
MAP3K5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 1776 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM
2 IC50 <= 100 nM