Brief Information of the Compound and Protein
Compound Name
15-(2-oxa-6-azaspiro[3.3]heptan-6-yl)-11-oxa-3,4,6,19,24-pentazatetracyclo[18.3.1.02,6.012,17]tetracosa-1(24),2,4,12(17),13,15,20,22-octaen-18-one
    Show/Hide
PubChem ID
CID: 142411981
Canonical SMILES
O=C1Nc2cccc(n2)-c2nncn2CCCCOc2ccc(cc12)N1CC2(COC2)C1
    Show/Hide
Compound Formula C23H24N6O3
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 5
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE11 family
Uniprot ID
Q99683
Gene Name
MAP3K5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 253 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 28 nM