Brief Information of the Compound and Protein
Compound Name
AZD-9291
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PubChem ID
CID: 71496458
SID: 163477648
Canonical SMILES
COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12
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Compound Formula C28H33N7O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
Q01279
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
GI50 = 2600 nM
   TI
   LI
   LO
   TS
2
IC50 = 81 nM
   TI
   LI
   LO
   TS