Brief Information of the Compound and Protein
Compound Name
N-[[2-(dimethylamino)pyridin-3-yl]methyl]-7-fluoro-4-hydroxy-12-methyl-2-oxo-1-azatricyclo[7.3.1.05,13]trideca-3,5,7,9(13)-tetraene-3-carboxamide
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PubChem ID
CID: 152550631
Canonical SMILES
CC1CCc2cc(F)cc3c(O)c(C(=O)NCc4cccnc4N(C)C)c(=O)n1c23
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Compound Formula C22H23FN4O3
Compound Structure
Protein Name
Toll-like receptor 2
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
O60603
Gene Name
TLR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000870 HEK-Blue Null1-v Homo sapiens (Human)  1
1
EC50 = 3200 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 3090 nM
   TI
   LI
   LO
   TS