Brief Information of the Compound and Protein
Compound Name
(6-((1H-pyrazolo[4,3-b] pyridin-3-yl)amino) benzo[d]isothiazol-3-yl) (4,4-difluoropiperidin-1-yl) methanone
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PubChem ID
CID: 122419163
Canonical SMILES
FC1(F)CCN(CC1)C(=O)c1nsc2cc(Nc3n[nH]c4cccnc34)ccc12
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Compound Formula C19H16F2N6OS
Compound Structure
Protein Name
Metabotropic glutamate receptor 4
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31423
Gene Name
GRM4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 139 nM
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