Brief Information of the Compound and Protein
Compound Name
3-[(1E)-1-[8-[(2-cyclopropyl-7-fluoroimidazo[1,2-a]pyridin-3-yl)methyl]-3-fluoro-6H-benzo[c][1]benzoxepin-11-ylidene]ethyl]-4H-1,2,4-oxadiazol-5-one
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PubChem ID
CID: 136491135
Canonical SMILES
C\C(c1noc(=O)[nH]1)=C1\c2ccc(Cc3c(nc4cc(F)ccn34)C3CC3)cc2COc2cc(F)ccc12
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Compound Formula C29H22F2N4O3
Compound Structure
Protein Name
Peroxisome proliferator-activated receptor gamma
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group C
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Nuclear hormone receptor subfamily 1 group C member 3
Uniprot ID
P37231
Gene Name
PPARG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  1
1
EC50 = 13 nM
   TI
   LI
   LO
   TS
CL000413 MKN45 Homo sapiens (Human)  1
1
EC50 = 1.7 nM
   TI
   LI
   LO
   TS