Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-[(6R)-4-amino-6-methyl-7H-pyrazolo[1,5-a]pyrazin-6-yl]phenyl]-5-cyanopyridine-2-carboxamide
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 PubChem ID
CID: 60194610
SID: 144200869
Canonical SMILES
C[C@]1(Cn2nccc2C(N)=N1)c1cccc(NC(=O)c2ccc(cn2)C#N)c1
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Compound Formula C20H17N7O
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000475 SK-N-BE(2)-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2.188 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.571 nM
2 IC50 = 4.6 nM