Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-N1-(3-(4-Methylpiperazin-1-yl)phenyl)-N3-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)malonamide
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 PubChem ID
CID: 141764057
Canonical SMILES
CN1CCN(c2cccc(NC(=O)CC(=O)Nc3ccc4c(/C=C/c5ccccn5)n[nH]c4c3)c2)CC1
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Compound Formula C28H29N7O2
Compound Structure
Protein Name
 Protein Info 
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  2
1
GI50 = 6170 nM
   TI
   LI
   LO
   TS
2
GI50 > 10000 nM
   TI
   LI
   LO
   TS