Brief Information of the Compound and Protein
Compound Name
(E)-1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)urea
    Show/Hide
PubChem ID
CID: 155534650
Canonical SMILES
O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1ccc2c(/C=C/c3ccccn3)n[nH]c2c1
    Show/Hide
Compound Formula C22H15ClF3N5O
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
GI50 = 1150 nM
   TI
   LI
   LO
   TS
2
GI50 = 1600 nM
   TI
   LI
   LO
   TS