Brief Information of the Compound and Protein
Compound Name
N1-(3-(3-Carbamoylphenyl)-1H-indazol-6-yl)-N3-(4-chloro-3-(trifluoromethyl)phenyl)malonamide
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PubChem ID
CID: 155514342
Canonical SMILES
NC(=O)c1cccc(-c2n[nH]c3cc(NC(=O)CC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)ccc23)c1
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Compound Formula C24H17ClF3N5O3
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
GI50 = 339 nM
   TI
   LI
   LO
   TS
2
GI50 = 1550 nM
   TI
   LI
   LO
   TS