Brief Information of the Compound and Protein
Compound Name
4-[7-cyclopentyloxy-2-(dimethylamino)-6-methoxyquinazolin-4-yl]-N,N-dimethylpiperazine-1-carboxamide
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PubChem ID
CID: 130472372
Canonical SMILES
COc1cc2c(nc(nc2cc1OC1CCCC1)N(C)C)N1CCN(CC1)C(=O)N(C)C
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Compound Formula C23H34N6O3
Compound Structure
Protein Name
Toll-like receptor 7
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NYK1
Gene Name
TLR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000870 HEK-Blue Null1-v Homo sapiens (Human)  1
1
IC50 = 17000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 17000 nM