Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CABOZANTINIB S-MALATE
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 PubChem ID
CID: 25102846
SID: 56424263
Canonical SMILES
COc1cc2nccc(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3)c2cc1OC.O=C(O)C[C@H](O)C(=O)O
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Compound Formula C32H30FN3O10
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 21.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.2 nM