Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-N'-[3-fluoro-4-[6-[2-hydroxy-3-(4-methylpiperazin-1-yl)propoxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
    Show/Hide
 PubChem ID
CID: 145981325
Canonical SMILES
CN1CCN(CC(O)COc2cn3ncnc(Oc4ccc(NC(=O)C5(CC5)C(=O)Nc5ccc(F)cc5)cc4F)c3c2C)CC1
    Show/Hide
Compound Formula C32H35F2N7O5
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 0.71 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.3 nM