Brief Information of the Compound and Protein
Compound Name
6-methyl-9-(4-methylphenyl)-13-(4-methylpiperazin-1-yl)-2,4,5,8,12,14-hexazatricyclo[8.4.0.03,7]tetradeca-1(14),3,6,8,10,12-hexaene
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PubChem ID
CID: 145987970
Canonical SMILES
CN1CCN(CC1)c1ncc2c(Nc3n[nH]c(C)c3N=C2c2ccc(C)cc2)n1
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Compound Formula C21H24N8
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 24.7 nM
   TI
   LI
   LO
   TS