Brief Information of the Compound and Protein
Compound Name
2-[(6-methylpyridin-3-yl)amino]-6-[(1R,4R)-5-prop-2-enoyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]pyridine-3-carboxamide
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PubChem ID
CID: 145982927
Canonical SMILES
Cc1ccc(Nc2nc(ccc2C(N)=O)N2C[C@H]3C[C@@H]2CN3C(=O)C=C)cn1
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Compound Formula C20H22N6O2
Compound Structure
Protein Name
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1 Homo sapiens (Human)  1
1
IC50 = 1.4 nM
   TI
   LI
   LO
   TS