Brief Information of the Compound and Protein
Compound Name
2-(4-(tert-Butyl)phenyl)-4-(4-(prop-2-yn-1-yl)piperazin-1-yl)-1H-benzo[d]imidazole
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PubChem ID
CID: 138978207
Canonical SMILES
C#CCN1CCN(c2cccc3[nH]c(-c4ccc(C(C)(C)C)cc4)nc23)CC1
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Compound Formula C24H28N4
Compound Structure
Protein Name
Gonadotropin-releasing hormone receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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GnRH receptor
Uniprot ID
P30968
Gene Name
GNRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  2
1
IC50 = 19952.62 nM
   TI
   LI
   LO
   TS
2
Ki = 395 nM
   TI
   LI
   LO
   TS