Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-formyl-N-[5-(trifluoromethyl)pyridin-2-yl]quinoline-8-carboxamide
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 PubChem ID
CID: 139187793
Canonical SMILES
FC(F)(F)c1ccc(NC(=O)c2cccc3ccc(C=O)nc23)nc1
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Compound Formula C17H10F3N3O2
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22455
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 2755 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  4
1
IC50 = 43 nM
   TI
   LI
   LO
   TS
2
IC50 = 57 nM
   TI
   LI
   LO
   TS
3
IC50 = 65 nM
   TI
   LI
   LO
   TS
4
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 57 nM
2 IC50 > 10000 nM