Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-Hydroxytamoxifen
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 PubChem ID
CID: 63062
Canonical SMILES
CCC(=C(c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
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Compound Formula C26H29NO2
Compound Structure
Protein Name
 Protein Info 
Estrogen receptor beta
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 2
Uniprot ID
Q92731
Gene Name
ESR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 21 nM
2 IC50 = 26.1 nM
3 IC50 = 32 nM
4 IC50 = 100 nM
5 Ki = 0.16 nM
6 Ki = 0.5 nM
7 Ki = 1.7 nM
8 Ki = 3.162 nM