Brief Information of the Compound and Protein
Compound Name
 Compound Info 
LY-2940680
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 PubChem ID
CID: 49848070
SID: 104176324
Canonical SMILES
CN(C1CCN(CC1)c1nnc(-c2ccnn2C)c2ccccc12)C(=O)c1ccc(F)cc1C(F)(F)F
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Compound Formula C26H24F4N6O
Compound Structure
Protein Name
 Protein Info 
Protein smoothened
Protein Classification
Membrane receptor
>
Frizzled family G protein-coupled receptor
>
Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001023 3T3/HH FlashII-7
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 1.18 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 2.4 nM
   TI
   LI
   LO
   TS