Brief Information of the Compound and Protein
Compound Name
tert-butyl (1S,5R)-3-[[4-(4-cyano-2-fluoroanilino)pyrimido[5,4-d]pyrimidin-8-yl]amino]-8-azabicyclo[3.2.1]octane-8-carboxylate
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Canonical SMILES
CC(C)(C)OC(=O)N1[C@H]2CC[C@@H]1C[C@@H](C2)Nc1ncnc2c(Nc3ccc(cc3F)C#N)ncnc12
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Compound Formula C25H27FN8O2
Compound Structure
Protein Name
Glucose-dependent insulinotropic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
Uniprot ID
Q8TDV5
Gene Name
GPR119
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 8.1 nM
   TI
   LI
   LO
   TS