Brief Information of the Compound and Protein
Compound Name
US8586600, II-1
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PubChem ID
CID: 25128184
SID: 56452457
Canonical SMILES
Cc1ccc(NC(=O)c2ccc(NC(=O)C=C)cc2)cc1Nc1nccc(n1)-c1cccnc1
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Compound Formula C26H22N6O2
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 2940 nM
   TI
   LI
   LO
   TS