Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
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 PubChem ID
CID: 60795
SID: 15103350
Canonical SMILES
Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl
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Compound Formula C23H27Cl2N3O2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
Ki = 89 nM
   TI
   LI
   LO
   TS
2
Ki = 90 nM
   TI
   LI
   LO
   TS
3
Ki = 199.53 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 574 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 318 nM
2 Ki > 1000 nM