Brief Information of the Compound and Protein
Compound Name
3-fluoro-4-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]benzoic acid
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PubChem ID
CID: 145968637
Canonical SMILES
CC(C)Nc1ccc2cnn(-c3cncc(n3)-c3ccc(cc3F)C(O)=O)c2c1
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Compound Formula C21H18FN5O2
Compound Structure
Protein Name
Serine/threonine-protein kinase pim-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase PIM family
Uniprot ID
P11309
Gene Name
PIM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 5400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 200 nM