Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(2-chloro-6-fluoroanilino)-7,7-dimethyl-N-[2-methyl-4-(trifluoromethyl)phenyl]-3,8-dihydrofuro[3,2-e]benzimidazole-5-carboxamide
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 PubChem ID
CID: 56970656
SID: 135691075
Canonical SMILES
Cc1cc(ccc1NC(=O)c1cc2nc(Nc3c(F)cccc3Cl)[nH]c2c2CC(C)(C)Oc12)C(F)(F)F
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Compound Formula C26H21ClF4N4O2
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 6.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 270 nM