Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(2-chloro-6-fluoroanilino)-1,7,7-trimethyl-N-[3-(trifluoromethyl)phenyl]-8H-furo[3,2-e]benzimidazole-5-carboxamide
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 PubChem ID
CID: 67503476
Canonical SMILES
Cn1c(Nc2c(F)cccc2Cl)nc2cc(C(=O)Nc3cccc(c3)C(F)(F)F)c3OC(C)(C)Cc3c12
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Compound Formula C26H21ClF4N4O2
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 5.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 405 nM
2 IC50 = 3180 nM