Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10807985, Compound 44
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 PubChem ID
CID: 118023034
Canonical SMILES
Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CCN(CC1)c1ncc(cn1)[C@@](C)(N)c1ccc(F)cc1
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Compound Formula C26H27FN10
Compound Structure
Protein Name
 Protein Info 
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  15
1
GI50 = 8 nM
   TI
   LI
   LO
   TS
2
GI50 = 17 nM
   TI
   LI
   LO
   TS
3
GI50 = 19 nM
   TI
   LI
   LO
   TS
4
GI50 = 28 nM
   TI
   LI
   LO
   TS
5
GI50 = 29 nM
   TI
   LI
   LO
   TS
6
GI50 = 34 nM
   TI
   LI
   LO
   TS
7
GI50 = 42 nM
   TI
   LI
   LO
   TS
8
GI50 = 69 nM
   TI
   LI
   LO
   TS
9
GI50 = 78 nM
   TI
   LI
   LO
   TS
10
GI50 = 117 nM
   TI
   LI
   LO
   TS
11
GI50 = 167 nM
   TI
   LI
   LO
   TS
12
GI50 = 292 nM
   TI
   LI
   LO
   TS
13
GI50 = 427 nM
   TI
   LI
   LO
   TS
14
GI50 = 751 nM
   TI
   LI
   LO
   TS
15
GI50 = 860 nM
   TI
   LI
   LO
   TS