Brief Information of the Compound and Protein
Compound Name
N-(5-((6,7-Dimethoxyquinolin-4-yl)oxy)pyridin-2-yl)-2-(1-isopropyl-1H-pyrazol-4-yl)acetamide
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PubChem ID
CID: 145966337
Canonical SMILES
COc1cc2nccc(Oc3ccc(NC(=O)Cc4cnn(C(C)C)c4)nc3)c2cc1OC
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Compound Formula C24H25N5O4
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  3
1
GI50 = 8 nM
   TI
   LI
   LO
   TS
2
GI50 = 150 nM
   TI
   LI
   LO
   TS
3
GI50 = 518 nM
   TI
   LI
   LO
   TS