Brief Information of the Compound and Protein
Compound Name
N-(4-((6,7-Dimethoxyquinazolin-4-yl)oxy)-2-methoxyphenyl)-2-(1-ethyl-1H-pyrazol-4-yl)acetamide
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PubChem ID
CID: 145971916
Canonical SMILES
CCn1cc(CC(=O)Nc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2OC)cn1
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Compound Formula C24H25N5O5
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  3
1
GI50 = 78 nM
   TI
   LI
   LO
   TS
2
GI50 = 86 nM
   TI
   LI
   LO
   TS
3
GI50 = 251 nM
   TI
   LI
   LO
   TS