Brief Information of the Compound and Protein
Compound Name
2-(4-(6,7-dimethoxyquinolin-4-yloxy)-2-methoxyphenyl)-N-(1-isopropyl-1H-pyrazol-4-yl)acetamide
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PubChem ID
CID: 145974728
Canonical SMILES
COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1CC(=O)Nc1cnn(C(C)C)c1
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Compound Formula C26H28N4O5
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  3
1
GI50 = 6 nM
   TI
   LI
   LO
   TS
2
GI50 = 7 nM
   TI
   LI
   LO
   TS
3
GI50 = 8 nM
   TI
   LI
   LO
   TS