Brief Information of the Compound and Protein
Compound Name
N-(4-((5,7-Dimethoxyquinazolin-4-yl)oxy)phenyl)-2-(4-isopropyl-1H-1,2,3-triazol-1-yl)acetamide
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PubChem ID
CID: 145968699
Canonical SMILES
COc1cc(OC)c2c(Oc3ccc(NC(=O)Cn4cc(C(C)C)nn4)cc3)ncnc2c1
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Compound Formula C23H24N6O4
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  3
1
GI50 = 7 nM
   TI
   LI
   LO
   TS
2
GI50 = 50 nM
   TI
   LI
   LO
   TS
3
GI50 = 55 nM
   TI
   LI
   LO
   TS