Brief Information of the Compound and Protein
Compound Name
2-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-N-(1-ethylpyrazol-4-yl)acetamide
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PubChem ID
CID: 11590120
SID: 16692633
Canonical SMILES
CCn1cc(NC(=O)Cc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2)cn1
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Compound Formula C23H23N5O4
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  3
1
GI50 = 7 nM
   TI
   LI
   LO
   TS
2
GI50 = 44 nM
   TI
   LI
   LO
   TS
3
GI50 = 488 nM
   TI
   LI
   LO
   TS