Brief Information of the Compound and Protein
Compound Name
Ripretinib
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PubChem ID
CID: 71584930
SID: 163637140
Canonical SMILES
CCn1c(=O)c(-c2cc(NC(=O)Nc3ccccc3)c(F)cc2Br)cc2cnc(NC)cc21
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Compound Formula C24H21BrFN5O2
Compound Structure
Protein Name
Platelet-derived growth factor receptor alpha
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P16234
Gene Name
PDGFRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
GI50 = 40 nM
   TI
   LI
   LO
   TS
2
GI50 = 188 nM
   TI
   LI
   LO
   TS