Brief Information of the Compound and Protein
Compound Name
US10807985, Compound 44
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PubChem ID
CID: 118023034
Canonical SMILES
Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CCN(CC1)c1ncc(cn1)[C@@](C)(N)c1ccc(F)cc1
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Compound Formula C26H27FN10
Compound Structure
Protein Name
Platelet-derived growth factor receptor alpha
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P16234
Gene Name
PDGFRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
GI50 = 10 nM
   TI
   LI
   LO
   TS
2
GI50 = 34 nM
   TI
   LI
   LO
   TS