Brief Information of the Compound and Protein
Compound Name
N-[3-[(E)-3-[4-[2-[6-methoxy-7-(2-methoxyethoxy)-3,4-dihydro-1H-isoquinolin-2-yl]ethoxy]phenyl]prop-2-enoyl]phenyl]quinoline-2-carboxamide
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PubChem ID
CID: 145978336
Canonical SMILES
COCCOc1cc2CN(CCOc3ccc(\C=C\C(=O)c4cccc(NC(=O)c5ccc6ccccc6n5)c4)cc3)CCc2cc1OC
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Compound Formula C40H39N3O6
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000781 MCF7/Topo Homo sapiens (Human)  1
1
IC50 = 2130 nM
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