Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carboxylic acid
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 PubChem ID
CID: 446916
SID: 14849614
Canonical SMILES
OC(=O)CCc1c([nH]c2cc(Cl)cc(Cl)c12)C(O)=O
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Compound Formula C12H9Cl2NO4
Compound Structure
Protein Name
 Protein Info 
Uracil nucleotide/cysteinyl leukotriene receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Leukotriene receptor
Uniprot ID
Q13304
Gene Name
GPR17
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 331 nM
   TI
   LI
   LO
   TS
2
EC50 = 812.83 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 6.31 nM
   TI
   LI
   LO
   TS
2
Ki = 2450 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 1210 nM
   TI
   LI
   LO
   TS
2
Ki = 2320 nM
   TI
   LI
   LO
   TS