Brief Information of the Compound and Protein
Compound Name
4-methoxy-N-[2-[2-(6-methoxypyridin-3-yl)tetrazol-5-yl]phenyl]benzamide
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PubChem ID
CID: 145975509
Canonical SMILES
COc1ccc(cc1)C(=O)Nc1ccccc1-c1nnn(n1)-c1ccc(OC)nc1
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Compound Formula C21H18N6O3
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  5
1
GI50 = 190 nM
   TI
   LI
   LO
   TS
2
GI50 = 202 nM
   TI
   LI
   LO
   TS
3
GI50 = 483 nM
   TI
   LI
   LO
   TS
4
GI50 = 802 nM
   TI
   LI
   LO
   TS
5
IC50 = 61.6 nM
   TI
   LI
   LO
   TS