Brief Information of the Compound and Protein
Compound Name
1-[3-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin-3- yl]ethynyl]phenyl]-5-methoxy- pyrazolo[3,4-b]pyridine- 3-carboxamide
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PubChem ID
CID: 117923582
Canonical SMILES
COc1cnc2n(nc(C(N)=O)c2c1)-c1cccc(c1)C#C[C@]1(O)CCN(C)C1=O
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Compound Formula C21H19N5O4
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 14
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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STE protein kinase group
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STE protein kinase unique family
Uniprot ID
Q99558
Gene Name
MAP3K14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 21 nM
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