Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[4-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin-3- yl]ethynyl]-2-pyridyl]indazole- 3-carboxamide
    Show/Hide
 PubChem ID
CID: 117923525
Canonical SMILES
CN1CC[C@@](O)(C#Cc2ccnc(c2)-n2nc(C(N)=O)c3ccccc23)C1=O
    Show/Hide
Compound Formula C20H17N5O3
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase kinase kinase 14
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase unique family
Uniprot ID
Q99558
Gene Name
MAP3K14
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS