Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8901310, Example 1
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 PubChem ID
CID: 24873449
SID: 50128583
Canonical SMILES
Cc1ncccc1NC(=O)c1ccc2c(CC[C@@H]3C[C@](O)(CC[C@@]23Cc2ccccc2)C(F)(F)F)c1
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Compound Formula C29H29F3N2O2
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000464 ChaGo-K-1
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 4.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.69 nM
   TI
   LI
   LO
   TS
3
IC50 = 8.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.31 nM
2 IC50 < 7.2 nM
3 IC50 = 35 nM