Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2,2-difluoro-N-[(1R,2S)-1-[1-(6-oxo-1-propylpyridin-3-yl)indazol-5-yl]oxy-1-phenylpropan-2-yl]propanamide
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 PubChem ID
CID: 145975057
Canonical SMILES
CCCn1cc(ccc1=O)-n1ncc2cc(O[C@@H]([C@H](C)NC(=O)C(C)(F)F)c3ccccc3)ccc12
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Compound Formula C27H28F2N4O3
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000464 ChaGo-K-1
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
2
IC50 = 256 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.7 nM