Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(1S,2R)-2-(2-bromo-4-cyanophenoxy)-1-cyclopropyl-2-(2-cyclopropylpyrimidin-5-yl)ethyl]-2,2,2-trifluoroacetamide
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 PubChem ID
CID: 145973741
Canonical SMILES
FC(F)(F)C(=O)N[C@H]([C@H](Oc1ccc(cc1Br)C#N)c1cnc(nc1)C1CC1)C1CC1
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Compound Formula C21H18BrF3N4O2
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000464 ChaGo-K-1
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
2
IC50 = 221 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14 nM
2 IC50 = 340 nM