Brief Information of the Compound and Protein
Compound Name
5-amino-3-[2-[4-[3-fluoro-4-(2-methoxyethoxy)phenyl]piperazin-1-yl]ethyl]-1-methyl-8-(1,3-thiazol-2-yl)-[1,2,4]triazolo[5,1-f]purin-2-one
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PubChem ID
CID: 145973260
Canonical SMILES
COCCOc1ccc(cc1F)N1CCN(CCn2c3nc(N)n4nc(nc4c3n(C)c2=O)-c2nccs2)CC1
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Compound Formula C25H29FN10O3S
Compound Structure
Protein Name
Nuclear receptor subfamily 1 group I member 2
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group I
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Nuclear hormone receptor subfamily 1 group I member 2
Uniprot ID
O75469
Gene Name
NR1I2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 > 60000 nM
   TI
   LI
   LO
   TS