Brief Information of the Compound and Protein
| Compound Name |
BDBM50242742
Show/Hide
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Epidermal growth factor receptor
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Protein Classification |
Enzyme
>
Kinase
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Protein Kinase
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TK protein kinase group
>
Tyrosine protein kinase EGFR family
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| Uniprot ID | Gene Name | EGFR |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000077 | Ba/F3 | Mus musculus (Mouse) | 3 |
| 1 |
GI50 = 340.7 nM
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TI
LI
LO
TS
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|---|---|---|---|
| 2 |
GI50 = 420 nM
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TI
LI
LO
TS
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| 3 |
GI50 = 560 nM
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TI
LI
LO
TS
|
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Biochemical Assays
| 1 | Kd = 3.4 nM | ||
|---|---|---|---|
| 2 | Kd = 7.1 nM | ||
| 3 | Kd = 46 nM | ||
| 4 | Kd = 72 nM | ||
| 5 | Kd = 79 nM | ||
| 6 | Kd = 81 nM | ||
| 7 | Kd = 98 nM | ||
| 8 | Kd = 110 nM | ||
| 9 | Kd = 180 nM | ||
| 10 | Kd = 400 nM | ||
| 11 | Kd = 1600 nM | ||
| 12 | Kd = 2000 nM | ||