Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-hydroxy-1-(3-methylbutanoyl)-3-[[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylamino]azetidine-3-carboxamide
    Show/Hide
 PubChem ID
CID: 130273583
Canonical SMILES
CC(C)CC(=O)N1CC(C1)(NS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO
    Show/Hide
Compound Formula C26H30N4O6S
Compound Structure
Protein Name
 Protein Info 
Disintegrin and metalloproteinase domain-containing protein 17
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MAM clan
>
Metallo protease M12B subfamily
Uniprot ID
P78536
Gene Name
ADAM17
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS