Brief Information of the Compound and Protein
Compound Name
1-[2-chloro-6-(cyclopropylmethoxy)pyridin-4-yl]-3-[(1,3-dimethyl-4-propan-2-ylpyrazolo[3,4-b]pyridin-6-yl)amino]urea
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PubChem ID
CID: 145966230
Canonical SMILES
CC(C)c1cc(NNC(=O)Nc2cc(Cl)nc(OCC3CC3)c2)nc2n(C)nc(C)c12
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Compound Formula C21H26ClN7O2
Compound Structure
Protein Name
Sphingosine 1-phosphate receptor 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
O95136
Gene Name
S1PR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1 Rattus norvegicus (Rat)  1
1
IC50 = 56.5 nM
   TI
   LI
   LO
   TS