Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
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 PubChem ID
CID: 449193
SID: 14879303
Canonical SMILES
FC(F)Oc1ccc(cc1OCC1CC1)C(=O)Nc1c(Cl)cncc1Cl
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Compound Formula C17H14Cl2F2N2O3
Compound Structure
Protein Name
 Protein Info 
3',5'-cyclic-AMP phosphodiesterase 4B
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 4
>
Phosphodiesterase 4B
Uniprot ID
Q07343
Gene Name
PDE4B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 0.3981 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.15 nM
2 IC50 = 0.2 nM
3 IC50 = 0.3981 nM
4 IC50 = 0.4 nM
5 IC50 = 0.49 nM
6 IC50 = 0.69 nM
7 IC50 = 0.7 nM
8 IC50 = 0.8 nM
9 IC50 = 0.84 nM
10 IC50 = 0.9 nM
11 IC50 = 1 nM
12 IC50 = 1.1 nM
13 IC50 = 1.3 nM