Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(4aR,6S,8aR)-2-amino-6-methyl-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-8a-yl]-N-(3-methoxyphenyl)-1,3-thiazole-5-carboxamide
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 PubChem ID
CID: 145978250
Canonical SMILES
COc1cccc(NC(=O)c2cnc(s2)[C@]23CO[C@@H](C)C[C@H]2CSC(N)=N3)c1
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Compound Formula C19H22N4O3S2
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000008 H4
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 0.11 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 270 nM